Death after Ondansetron in dogs

216 reports to the FDA describe death in dogs given Ondansetron. That is 32% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

216Reports
99%Marked serious
0.0%Recovered
100%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
41 22%
1–2 days
33 18%
3–7 days
20 11%
1–4 weeks
38 21%
Over a month
52 28%

How the animals did

Died
70 32%
Euthanised
145 67%
Not known
1 0.5%

Problems reported at the same time

Age of the animals

Under 1 year
32
1–3 years
25
4–7 years
52
8–11 years
68
12+ years
36

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause death in dogs?
216 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with death