Kidney problems after Ondansetron in dogs

The FDA has received 150 reports of kidney problems in dogs after Ondansetron. That is 23% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

150Reports
87%Marked serious
8.0%Recovered
50%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
26 21%
1–2 days
22 18%
3–7 days
14 11%
1–4 weeks
28 23%
Over a month
32 26%

How the animals did

Recovered
12 8.0%
Still unwell when reported
46 31%
Died
16 11%
Euthanised
59 39%
Not known
17 11%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
20
4–7 years
41
8–11 years
43
12+ years
36

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause kidney problems in dogs?
150 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with kidney problems