Collapse after Ondansetron in dogs

The FDA has received 29 reports of collapse in dogs after Ondansetron. That is 4.4% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports
93%Marked serious
21%Recovered
38%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
8 31%
1–2 days
4 15%
3–7 days
1 3.8%
1–4 weeks
2 7.7%
Over a month
11 42%

How the animals did

Recovered
6 21%
Still unwell when reported
11 38%
Died
4 14%
Euthanised
7 24%
Not known
1 3.4%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
7
8–11 years
10
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause collapse in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with collapse