Liver problems after Omeprazole in dogs

231 reports to the FDA describe liver problems in dogs given Omeprazole. That is 24% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

231Reports
76%Marked serious
7.8%Recovered
35%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
23 12%
1–2 days
26 14%
3–7 days
23 12%
1–4 weeks
59 31%
Over a month
59 31%

How the animals did

Recovered
18 7.8%
Still unwell when reported
103 45%
Died
19 8.2%
Euthanised
62 27%
Not known
29 13%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
25
4–7 years
60
8–11 years
78
12+ years
63

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause liver problems in dogs?
231 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Omeprazole in dogs · Medicines most reported with liver problems