Abdominal mass after Oclacitinib (Apoquel) in dogs

The FDA has received 82 reports of abdominal mass in dogs after Oclacitinib. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

82Reports

89%Marked serious

1.2%Recovered

54%Died or euthanised

92 daysTypical onset

How soon it started

Same day

2 4.0%

1–2 days

2 4.0%

3–7 days

1 2.0%

1–4 weeks

8 16%

Over a month

37 74%

How the animals did

Recovered

1 1.2%

Still unwell when reported

29 35%

Died

6 7.3%

Euthanised

38 46%

Not known

8 9.8%

Problems reported at the same time

Death

43 52%

Abnormal radiograph finding

29 35%

Abnormal ultrasound finding

28 34%

26 32%

25 30%

24 29%

21 26%

16 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause abdominal mass in dogs?: 82 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 92 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abdominal mass with similar medicines

Abdominal mass after Cyclosporine (Atopica) 20 reports · 0.1% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with abdominal mass