Neomycin + Polymyxin B side effects in dogs

195 reports sent to the FDA between 1995 and 2026 involve Neomycin + Polymyxin B in dogs. The most reported problems were vomiting, corneal ulcer, loss of appetite. 53% were marked serious, and where it was recorded, signs eased after stopping the medicine in 50% of cases.

195Reports
53%Marked serious
14%Only medicine involved
16%Recovered
9.2%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

52 27%
31 16%
29 15%
Schirmer tear test
19 9.7%
Wobbliness (ataxia)
18 9.2%
Corneal disorder
18 9.2%
Squinting
18 9.2%
Swelling
17 8.7%
Eye disorder (for photophobia see 'neurological')
17 8.7%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
8 4.1%
Didn't stop fleas
3 1.5%
Didn't stop worms
3 1.5%

How soon problems started

Same day
38 27%
1–2 days
14 10%
3–7 days
21 15%
1–4 weeks
28 20%
Over a month
39 28%

Time from the first dose to the first sign, where both dates were reported (140 reports).

How the animals did

Recovered
30 15%
Recovered with lasting effects
2 1.0%
Still unwell when reported
59 30%
Died
9 4.6%
Euthanised
9 4.6%
Not known
86 44%

Breeds named most often

Popular breeds appear more often because there are more of them.

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