Behaviour change after Neomycin + Polymyxin B in dogs

The FDA has received 21 reports of behaviour change in dogs after Neomycin + Polymyxin B. That is 11% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can Neomycin + Polymyxin B cause behaviour change in dogs?

21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 11 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

• Behaviour change after Melarsomine (Immiticide) 278 reports · 1.2% of its reports
• Behaviour change after Polysulfated Glycosaminoglycan 178 reports · 3.3% of its reports
• Behaviour change after Diphenhydramine 251 reports · 5.3% of its reports
• Behaviour change after Butorphanol 151 reports · 3.4% of its reports
• Behaviour change after Cefpodoxime 162 reports · 4.0% of its reports
• Behaviour change after Tramadol 192 reports · 5.1% of its reports
• Behaviour change after Florfenicol + Mometasone + Terbinafine 339 reports · 9.6% of its reports
• Behaviour change after Desoxycorticosterone Pivalate 174 reports · 5.2% of its reports
• Behaviour change after Propofol 71 reports · 2.3% of its reports
• Behaviour change after Dirlotapide 107 reports · 3.8% of its reports

All reported side effects of Neomycin + Polymyxin B in dogs · Medicines most reported with behaviour change