Liver problems after Methylprednisolone in dogs

94 reports to the FDA describe liver problems in dogs given Methylprednisolone. That is 14% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

94Reports
35%Marked serious
2.1%Recovered
27%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
8 17%
1–2 days
3 6.5%
3–7 days
8 17%
1–4 weeks
8 17%
Over a month
19 41%

How the animals did

Recovered
2 2.1%
Still unwell when reported
31 33%
Died
12 13%
Euthanised
13 14%
Not known
36 38%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
17
4–7 years
21
8–11 years
39
12+ years
13

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause liver problems in dogs?
94 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Methylprednisolone in dogs · Medicines most reported with liver problems