Not himself/herself after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) in dogs

26 reports to the FDA describe not himself/herself in dogs given Lufenuron + Milbemycin Oxime + Praziquantel. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

26Reports
46%Marked serious
31%Recovered
12%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
7 54%
1–2 days
2 15%
3–7 days
0 0.0%
1–4 weeks
1 7.7%
Over a month
3 23%

How the animals did

Recovered
8 31%
Still unwell when reported
13 50%
Died
3 12%
Not known
2 7.7%

Problems reported at the same time

15 58%
4 15%
3 12%
Sleepiness - systemic disorder
3 12%

Age of the animals

Under 1 year
3
1–3 years
6
4–7 years
9
8–11 years
3
12+ years
4

About this medicine

Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly). Praziquantel treats tapeworms.

Products with this combination include Sentinel Spectrum. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lufenuron + Milbemycin Oxime + Praziquantel cause not himself/herself in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not himself/herself with similar medicines

All reported side effects of Lufenuron + Milbemycin Oxime + Praziquantel in dogs · Medicines most reported with not himself/herself