Nausea after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) in dogs

31 reports to the FDA describe nausea in dogs given Lufenuron + Milbemycin Oxime + Praziquantel. That is 0.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

31Reports
48%Marked serious
48%Recovered
0.0%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
16 67%
1–2 days
2 8.3%
3–7 days
0 0.0%
1–4 weeks
3 13%
Over a month
3 13%

How the animals did

Recovered
15 48%
Still unwell when reported
6 19%
Not known
10 32%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
10
4–7 years
10
8–11 years
4
12+ years
2

About this medicine

Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly). Praziquantel treats tapeworms.

Products with this combination include Sentinel Spectrum. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lufenuron + Milbemycin Oxime + Praziquantel cause nausea in dogs?
31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Nausea with similar medicines

All reported side effects of Lufenuron + Milbemycin Oxime + Praziquantel in dogs · Medicines most reported with nausea