Weight loss after Lokivetmab (Cytopoint) in dogs

214 reports to the FDA describe weight loss in dogs given Lokivetmab. That is 3.3% of all reports for this medicine, compared with 1.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

214Reports

64%Marked serious

1.4%Recovered

18%Died or euthanised

20 daysTypical onset

How soon it started

Same day

32 21%

1–2 days

11 7.4%

3–7 days

15 10%

1–4 weeks

31 21%

Over a month

60 40%

How the animals did

Recovered

3 1.4%

Still unwell when reported

146 68%

Died

19 8.9%

Euthanised

20 9.3%

Not known

26 12%

Problems reported at the same time

Loss of appetite

109 51%

Lethargy

91 43%

Vomiting

75 35%

Didn't work as expected

66 31%

50 23%

45 21%

40 19%

39 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause weight loss in dogs?: 214 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

Weight loss after Bedinvetmab (Librela) 723 reports · 3.7% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with weight loss