Weight loss after Bedinvetmab (Librela) in dogs

The FDA has received 723 reports of weight loss in dogs after Bedinvetmab. That is 3.7% of all reports for this medicine, compared with 1.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

723Reports

82%Marked serious

2.1%Recovered

34%Died or euthanised

13 daysTypical onset

How soon it started

Same day

128 20%

1–2 days

94 15%

3–7 days

61 9.7%

1–4 weeks

137 22%

Over a month

207 33%

How the animals did

Recovered

14 1.9%

Recovered with lasting effects

1 0.1%

Still unwell when reported

388 54%

Died

69 9.5%

Euthanised

180 25%

Not known

71 9.8%

Problems reported at the same time

382 53%

248 34%

204 28%

193 27%

157 22%

156 22%

145 20%

137 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

279

12+ years

357

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause weight loss in dogs?: 723 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

Weight loss after Lokivetmab (Cytopoint) 214 reports · 3.3% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with weight loss