Death after Bedinvetmab (Librela) in dogs

The FDA has received 3,841 reports of death in dogs after Bedinvetmab. That is 20% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

3,841Reports

99%Marked serious

0.0%Recovered

100%Died or euthanised

7 daysTypical onset

How soon it started

Same day

747 22%

1–2 days

565 17%

3–7 days

486 14%

1–4 weeks

707 21%

Over a month

918 27%

How the animals did

Still unwell when reported

2 0.1%

Died

1,327 35%

Euthanised

2,508 65%

Not known

4 0.1%

Problems reported at the same time

1,035 27%

719 19%

626 16%

624 16%

610 16%

606 16%

529 14%

459 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

177

8–11 years

1,174

12+ years

1,980

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause death in dogs?: 3,841 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Lokivetmab (Cytopoint) 460 reports · 7.1% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with death