Death after Lokivetmab (Cytopoint) in dogs

The FDA has received 460 reports of death in dogs after Lokivetmab. That is 7.1% of all reports for this medicine, compared with 5.2% across reports for all dog medicines.

460Reports

100%Marked serious

0.0%Recovered

100%Died or euthanised

7 daysTypical onset

How soon it started

Same day

86 23%

1–2 days

49 13%

3–7 days

50 14%

1–4 weeks

75 20%

Over a month

109 30%

How the animals did

Died

203 44%

Euthanised

257 56%

Problems reported at the same time

168 37%

157 34%

146 32%

110 24%

96 21%

89 19%

82 18%

67 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

169

12+ years

136

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause death in dogs?: 460 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Bedinvetmab (Librela) 3,841 reports · 20% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with death