Kidney problems after Lokivetmab (Cytopoint) in dogs

248 reports to the FDA describe kidney problems in dogs given Lokivetmab. That is 3.8% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

248Reports

81%Marked serious

3.2%Recovered

36%Died or euthanised

11 daysTypical onset

How soon it started

Same day

43 22%

1–2 days

27 14%

3–7 days

19 9.8%

1–4 weeks

39 20%

Over a month

66 34%

How the animals did

Recovered

8 3.2%

Still unwell when reported

122 49%

Died

28 11%

Euthanised

61 25%

Not known

29 12%

Problems reported at the same time

114 46%

113 46%

109 44%

94 38%

89 36%

56 23%

49 20%

Didn't work as expected

47 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause kidney problems in dogs?: 248 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Bedinvetmab (Librela) 1,332 reports · 6.8% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with kidney problems