Didn't work as expected after Lokivetmab (Cytopoint) in dogs

2,202 reports to the FDA describe didn't work as expected in dogs given Lokivetmab. That is 34% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported unusually often with this medicine.

2,202Reports
36%Marked serious
5.6%Recovered
2.8%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
320 24%
1–2 days
116 8.8%
3–7 days
61 4.6%
1–4 weeks
254 19%
Over a month
569 43%

How the animals did

Recovered
122 5.5%
Recovered with lasting effects
1 0.0%
Still unwell when reported
1,645 75%
Died
27 1.2%
Euthanised
35 1.6%
Not known
372 17%

Problems reported at the same time

Age of the animals

Under 1 year
25
1–3 years
423
4–7 years
752
8–11 years
650
12+ years
251

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause didn't work as expected in dogs?
2,202 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with didn't work as expected