Didn't work as expected after Bedinvetmab (Librela) in dogs

2,344 reports to the FDA describe didn't work as expected in dogs given Bedinvetmab. That is 12% of all reports for this medicine, compared with 13% across reports for all dog medicines.

2,344Reports

45%Marked serious

3.5%Recovered

10%Died or euthanised

23 daysTypical onset

How soon it started

Same day

351 18%

1–2 days

80 4.0%

3–7 days

91 4.6%

1–4 weeks

565 28%

Over a month

897 45%

How the animals did

Recovered

79 3.4%

Recovered with lasting effects

3 0.1%

Still unwell when reported

1,627 69%

Died

69 2.9%

Euthanised

166 7.1%

Not known

400 17%

Problems reported at the same time

233 9.9%

202 8.6%

195 8.3%

167 7.1%

165 7.0%

145 6.2%

144 6.1%

134 5.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

167

8–11 years

808

12+ years

1,177

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause didn't work as expected in dogs?: 2,344 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Lokivetmab (Cytopoint) 2,202 reports · 34% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with didn't work as expected