Liver problems after Bedinvetmab (Librela) in dogs

1,579 reports to the FDA describe liver problems in dogs given Bedinvetmab. That is 8.0% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,579Reports

78%Marked serious

3.9%Recovered

26%Died or euthanised

17 daysTypical onset

How soon it started

Same day

213 16%

1–2 days

152 11%

3–7 days

165 12%

1–4 weeks

332 25%

Over a month

468 35%

How the animals did

Recovered

56 3.5%

Recovered with lasting effects

5 0.3%

Still unwell when reported

991 63%

Died

87 5.5%

Euthanised

325 21%

Not known

115 7.3%

Problems reported at the same time

560 35%

463 29%

411 26%

411 26%

387 25%

296 19%

257 16%

257 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

101

8–11 years

609

12+ years

841

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause liver problems in dogs?: 1,579 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Lokivetmab (Cytopoint) 559 reports · 8.6% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with liver problems