Excessive thirst after Bedinvetmab (Librela) in dogs

The FDA has received 1,877 reports of excessive thirst in dogs after Bedinvetmab. That is 9.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,877Reports

52%Marked serious

8.2%Recovered

15%Died or euthanised

9 daysTypical onset

How soon it started

Same day

342 20%

1–2 days

255 15%

3–7 days

227 14%

1–4 weeks

416 25%

Over a month

434 26%

How the animals did

Recovered

145 7.7%

Recovered with lasting effects

8 0.4%

Still unwell when reported

1,204 64%

Died

74 3.9%

Euthanised

204 11%

Not known

242 13%

Problems reported at the same time

1,371 73%

357 19%

349 19%

296 16%

277 15%

273 15%

246 13%

Inappropriate urination

228 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

634

12+ years

1,073

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause excessive thirst in dogs?: 1,877 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Lokivetmab (Cytopoint) 234 reports · 3.6% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with excessive thirst