Itching after Lokivetmab (Cytopoint) in dogs

The FDA has received 537 reports of itching in dogs after Lokivetmab. That is 8.2% of all reports for this medicine, compared with 4.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

537Reports

43%Marked serious

18%Recovered

3.9%Died or euthanised

10 daysTypical onset

How soon it started

Same day

126 30%

1–2 days

36 8.5%

3–7 days

38 8.9%

1–4 weeks

66 16%

Over a month

159 37%

How the animals did

Recovered

96 18%

Recovered with lasting effects

1 0.2%

Still unwell when reported

307 57%

Died

8 1.5%

Euthanised

13 2.4%

Not known

112 21%

Problems reported at the same time

Didn't work as expected

175 33%

119 22%

108 20%

96 18%

83 15%

81 15%

Skin rash or irritation

73 14%

Skin redness

72 13%

Age of the animals

Under 1 year

1–3 years

133

4–7 years

173

8–11 years

135

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause itching in dogs?: 537 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

Itching after Bedinvetmab (Librela) 554 reports · 2.8% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with itching