Loss of appetite after Lokivetmab (Cytopoint) in dogs

The FDA has received 1,040 reports of loss of appetite in dogs after Lokivetmab. That is 16% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,040Reports
58%Marked serious
12%Recovered
16%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
208 25%
1–2 days
161 19%
3–7 days
117 14%
1–4 weeks
132 16%
Over a month
218 26%

How the animals did

Recovered
120 12%
Recovered with lasting effects
3 0.3%
Still unwell when reported
645 62%
Died
70 6.7%
Euthanised
99 9.5%
Not known
103 9.9%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
160
4–7 years
312
8–11 years
359
12+ years
176

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause loss of appetite in dogs?
1,040 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with loss of appetite