Diarrhea after Lokivetmab (Cytopoint) in dogs

The FDA has received 734 reports of diarrhea in dogs after Lokivetmab. That is 11% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

734Reports
53%Marked serious
19%Recovered
8.9%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
189 32%
1–2 days
115 19%
3–7 days
73 12%
1–4 weeks
98 16%
Over a month
120 20%

How the animals did

Recovered
137 19%
Recovered with lasting effects
1 0.1%
Still unwell when reported
459 63%
Died
27 3.7%
Euthanised
38 5.2%
Not known
72 9.8%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
170
4–7 years
234
8–11 years
199
12+ years
101

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause diarrhea in dogs?
734 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with diarrhea