Excessive urination after Lokivetmab (Cytopoint) in dogs

189 reports to the FDA describe excessive urination in dogs given Lokivetmab. That is 2.9% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

189Reports
42%Marked serious
7.4%Recovered
4.8%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
25 18%
1–2 days
20 15%
3–7 days
14 10%
1–4 weeks
26 19%
Over a month
52 38%

How the animals did

Recovered
12 6.3%
Recovered with lasting effects
2 1.1%
Still unwell when reported
144 76%
Died
3 1.6%
Euthanised
6 3.2%
Not known
22 12%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
20
4–7 years
53
8–11 years
71
12+ years
43

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause excessive urination in dogs?
189 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with excessive urination