Inappropriate urination after Lokivetmab (Cytopoint) in dogs

101 reports to the FDA describe inappropriate urination in dogs given Lokivetmab. That is 1.6% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

101Reports

65%Marked serious

9.9%Recovered

19%Died or euthanised

4 daysTypical onset

How soon it started

Same day

26 30%

1–2 days

10 12%

3–7 days

8 9.3%

1–4 weeks

10 12%

Over a month

32 37%

How the animals did

Recovered

9 8.9%

Recovered with lasting effects

1 1.0%

Still unwell when reported

58 57%

Died

8 7.9%

Euthanised

11 11%

Not known

14 14%

Problems reported at the same time

30 30%

26 26%

25 25%

24 24%

21 21%

18 18%

16 16%

15 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause inappropriate urination in dogs?: 101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate urination with similar medicines

Inappropriate urination after Bedinvetmab (Librela) 744 reports · 3.8% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with inappropriate urination