Urinary incontinence after Lokivetmab (Cytopoint) in dogs

113 reports to the FDA describe urinary incontinence in dogs given Lokivetmab. That is 1.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

113Reports
48%Marked serious
3.5%Recovered
17%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
18 20%
1–2 days
12 13%
3–7 days
14 16%
1–4 weeks
18 20%
Over a month
27 30%

How the animals did

Recovered
4 3.5%
Still unwell when reported
75 66%
Died
10 8.8%
Euthanised
9 8.0%
Not known
15 13%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
10
4–7 years
15
8–11 years
46
12+ years
40

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause urinary incontinence in dogs?
113 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with urinary incontinence