Liver problems after Lidocaine in dogs

43 reports to the FDA describe liver problems in dogs given Lidocaine. That is 18% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports
81%Marked serious
2.3%Recovered
47%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
7 18%
1–2 days
14 36%
3–7 days
7 18%
1–4 weeks
5 13%
Over a month
6 15%

How the animals did

Recovered
1 2.3%
Still unwell when reported
12 28%
Died
9 21%
Euthanised
11 26%
Not known
10 23%

Problems reported at the same time

23 53%
20 47%
20 47%
17 40%
Neutrophilia
14 33%

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
13
8–11 years
16
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Lidocaine cause liver problems in dogs?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Lidocaine in dogs · Medicines most reported with liver problems