Urinary tract infection after Leptospirosis Vaccine in dogs

The FDA has received 84 reports of urinary tract infection in dogs after Leptospirosis Vaccine. That is 1.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

84Reports
71%Marked serious
4.8%Recovered
24%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
14 27%
1–2 days
6 12%
3–7 days
10 19%
1–4 weeks
8 15%
Over a month
14 27%

How the animals did

Recovered
3 3.6%
Recovered with lasting effects
1 1.2%
Still unwell when reported
37 44%
Died
6 7.1%
Euthanised
14 17%
Not known
23 27%

Problems reported at the same time

Liver problems
38 45%
Vomiting
37 44%
Lethargy
35 42%
Loss of appetite
35 42%
Kidney problems
29 35%
Didn't work as expected
20 24%
Death
20 24%
Diarrhea
20 24%

Age of the animals

Under 1 year
9
1–3 years
8
4–7 years
23
8–11 years
22
12+ years
21

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause urinary tract infection in dogs?
84 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary tract infection with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with urinary tract infection