Urinary incontinence after Leptospirosis Vaccine in dogs

The FDA has received 85 reports of urinary incontinence in dogs after Leptospirosis Vaccine. That is 1.1% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

85Reports
68%Marked serious
15%Recovered
21%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
15 21%
1–2 days
15 21%
3–7 days
10 14%
1–4 weeks
12 16%
Over a month
21 29%

How the animals did

Recovered
13 15%
Still unwell when reported
41 48%
Died
4 4.7%
Euthanised
14 16%
Not known
13 15%

Problems reported at the same time

Vomiting
23 27%
Lethargy
22 26%
Loss of appetite
21 25%
Death
18 21%
Wobbliness (ataxia)
17 20%
Excessive urination
15 18%
Excessive thirst
15 18%
Liver problems
15 18%

Age of the animals

Under 1 year
20
1–3 years
7
4–7 years
17
8–11 years
23
12+ years
18

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause urinary incontinence in dogs?
85 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with urinary incontinence