Quiet after Leptospirosis Vaccine in dogs

The FDA has received 44 reports of quiet in dogs after Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports

77%Marked serious

20%Recovered

18%Died or euthanised

4 daysTypical onset

How soon it started

Same day

14 37%

1–2 days

4 11%

3–7 days

3 7.9%

1–4 weeks

2 5.3%

Over a month

15 39%

How the animals did

Recovered

9 20%

Still unwell when reported

19 43%

Died

3 6.8%

Euthanised

5 11%

Not known

8 18%

Problems reported at the same time

27 61%

25 57%

17 39%

11 25%

10 23%

Didn't work as expected

10 23%

Allergic reaction

9 20%

Liver problems

8 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause quiet in dogs?: 44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Quiet with similar medicines

Quiet after Rabies Vaccine 31 reports · 0.3% of its reports
Quiet after Bordetella Vaccine 29 reports · 0.3% of its reports
Quiet after Distemper-parvo Vaccine 24 reports · 0.4% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with quiet