Low blood pressure after Leptospirosis Vaccine in dogs

The FDA has received 42 reports of low blood pressure in dogs after Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

42Reports

100%Marked serious

40%Recovered

29%Died or euthanised

Same dayTypical onset

How soon it started

Same day

25 69%

1–2 days

2 5.6%

3–7 days

1 2.8%

1–4 weeks

3 8.3%

Over a month

5 14%

How the animals did

Recovered

17 40%

Still unwell when reported

10 24%

Died

4 9.5%

Euthanised

8 19%

Not known

3 7.1%

Problems reported at the same time

33 79%

28 67%

23 55%

16 38%

12 29%

12 29%

9 21%

9 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause low blood pressure in dogs?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low blood pressure with similar medicines

Low blood pressure after Rabies Vaccine 57 reports · 0.6% of its reports
Low blood pressure after Bordetella Vaccine 55 reports · 0.6% of its reports
Low blood pressure after Distemper-parvo Vaccine 31 reports · 0.5% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with low blood pressure