Hyperglycaemia after Leptospirosis Vaccine in dogs

106 reports to the FDA describe hyperglycaemia in dogs given Leptospirosis Vaccine. That is 1.3% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

106Reports

83%Marked serious

14%Recovered

27%Died or euthanised

3 daysTypical onset

How soon it started

Same day

29 34%

1–2 days

12 14%

3–7 days

9 11%

1–4 weeks

19 22%

Over a month

16 19%

How the animals did

Recovered

15 14%

Still unwell when reported

43 41%

Died

8 7.5%

Euthanised

21 20%

Not known

19 18%

Problems reported at the same time

61 58%

50 47%

47 44%

39 37%

38 36%

34 32%

31 29%

31 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause hyperglycaemia in dogs?: 106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperglycaemia with similar medicines

Hyperglycaemia after Rabies Vaccine 139 reports · 1.4% of its reports
Hyperglycaemia after Bordetella Vaccine 122 reports · 1.3% of its reports
Hyperglycaemia after Lyme Vaccine 24 reports · 0.3% of its reports
Hyperglycaemia after Distemper-parvo Vaccine 91 reports · 1.4% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with hyperglycaemia