Elevated temperature after Leptospirosis Vaccine in dogs

123 reports to the FDA describe elevated temperature in dogs given Leptospirosis Vaccine. That is 1.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

123Reports
72%Marked serious
37%Recovered
11%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
57 55%
1–2 days
7 6.8%
3–7 days
8 7.8%
1–4 weeks
15 15%
Over a month
16 16%

How the animals did

Recovered
43 35%
Recovered with lasting effects
2 1.6%
Still unwell when reported
43 35%
Died
5 4.1%
Euthanised
8 6.5%
Not known
22 18%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
43
4–7 years
32
8–11 years
20
12+ years
7

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause elevated temperature in dogs?
123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated temperature with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with elevated temperature