Discomfort after Leptospirosis Vaccine in dogs

The FDA has received 40 reports of discomfort in dogs after Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports

75%Marked serious

23%Recovered

10%Died or euthanised

1 daysTypical onset

How soon it started

Same day

14 40%

1–2 days

6 17%

3–7 days

5 14%

1–4 weeks

3 8.6%

Over a month

7 20%

How the animals did

Recovered

9 23%

Still unwell when reported

19 48%

Died

2 5.0%

Euthanised

2 5.0%

Not known

8 20%

Problems reported at the same time

19 48%

17 43%

13 33%

10 25%

8 20%

8 20%

Injection site reaction

7 18%

Vocalising

6 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause discomfort in dogs?: 40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Discomfort with similar medicines

Discomfort after Rabies Vaccine 40 reports · 0.4% of its reports
Discomfort after Bordetella Vaccine 39 reports · 0.4% of its reports
Discomfort after Distemper-parvo Vaccine 23 reports · 0.4% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with discomfort