Decreased body temperature after Leptospirosis Vaccine in dogs

26 reports to the FDA describe decreased body temperature in dogs given Leptospirosis Vaccine. That is 0.3% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports
88%Marked serious
35%Recovered
23%Died or euthanised
15 daysTypical onset
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How soon it started

Same day
8 40%
1–2 days
1 5.0%
3–7 days
0 0.0%
1–4 weeks
5 25%
Over a month
6 30%

How the animals did

Recovered
9 35%
Still unwell when reported
7 27%
Died
2 7.7%
Euthanised
4 15%
Not known
4 15%

Problems reported at the same time

Vomiting
17 65%
Lethargy
14 54%
Allergic reaction
10 38%
Diarrhea
9 35%
Pale mucous membrane
9 35%
Liver problems
8 31%
Loss of appetite
8 31%
Death
6 23%

Age of the animals

Under 1 year
6
1–3 years
10
4–7 years
5
8–11 years
3
12+ years
2

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause decreased body temperature in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 15 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased body temperature with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with decreased body temperature