Blood in stool after Leptospirosis Vaccine in dogs

The FDA has received 50 reports of blood in stool in dogs after Leptospirosis Vaccine. That is 0.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

50Reports

80%Marked serious

4.0%Recovered

34%Died or euthanised

14 daysTypical onset

How soon it started

Same day

12 28%

1–2 days

6 14%

3–7 days

3 7.0%

1–4 weeks

11 26%

Over a month

11 26%

How the animals did

Recovered

2 4.0%

Still unwell when reported

24 48%

Died

5 10%

Euthanised

12 24%

Not known

7 14%

Problems reported at the same time

27 54%

26 52%

25 50%

24 48%

23 46%

17 34%

15 30%

14 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause blood in stool in dogs?: 50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in stool with similar medicines

Blood in stool after Rabies Vaccine 70 reports · 0.7% of its reports
Blood in stool after Bordetella Vaccine 65 reports · 0.7% of its reports
Blood in stool after Distemper-parvo Vaccine 39 reports · 0.6% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with blood in stool