Arthritis after Leptospirosis Vaccine in dogs

The FDA has received 24 reports of arthritis in dogs after Leptospirosis Vaccine. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

67%Marked serious

8.3%Recovered

17%Died or euthanised

–Typical onset

How the animals did

Recovered

1 4.2%

Recovered with lasting effects

1 4.2%

Still unwell when reported

13 54%

Died

2 8.3%

Euthanised

2 8.3%

Not known

5 21%

Problems reported at the same time

Didn't work as expected

8 33%

8 33%

7 29%

6 25%

6 25%

5 21%

4 17%

4 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause arthritis in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Arthritis with similar medicines

Arthritis after Rabies Vaccine 32 reports · 0.3% of its reports
Arthritis after Bordetella Vaccine 25 reports · 0.3% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with arthritis