Dental calculus after Leptospirosis Vaccine in dogs

35 reports to the FDA describe dental calculus in dogs given Leptospirosis Vaccine. That is 0.4% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

35Reports

57%Marked serious

0.0%Recovered

20%Died or euthanised

242 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

1 5.6%

3–7 days

2 11%

1–4 weeks

2 11%

Over a month

13 72%

How the animals did

Still unwell when reported

10 29%

Died

4 11%

Euthanised

3 8.6%

Not known

18 51%

Problems reported at the same time

14 40%

14 40%

13 37%

12 34%

11 31%

11 31%

Didn't work as expected

9 26%

Didn't prevent heartworm

8 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause dental calculus in dogs?: 35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 242 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dental calculus with similar medicines

Dental calculus after Rabies Vaccine 37 reports · 0.4% of its reports
Dental calculus after Bordetella Vaccine 35 reports · 0.4% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with dental calculus