Seizures after Keppra in dogs

The FDA has received 116 reports of seizures in dogs after Keppra. That is 65% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

116Reports
99%Marked serious
9.5%Recovered
34%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
22 23%
1–2 days
14 14%
3–7 days
11 11%
1–4 weeks
23 24%
Over a month
27 28%

How the animals did

Recovered
11 9.5%
Still unwell when reported
59 51%
Died
11 9.5%
Euthanised
29 25%
Not known
6 5.2%

Problems reported at the same time

40 34%
Tremors
17 15%
Diarrhea
12 10%
Wobbliness (ataxia)
12 10%
Collapse
11 9.5%
10 8.6%
Loss of appetite
10 8.6%

Age of the animals

Under 1 year
1
1–3 years
20
4–7 years
18
8–11 years
35
12+ years
41

About this medicine

Type: medicine.

Questions owners ask

Can Keppra cause seizures in dogs?
116 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Keppra in dogs · Medicines most reported with seizures