Death after Keppra in dogs

The FDA has received 49 reports of death in dogs after Keppra. That is 27% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

49Reports
100%Marked serious
0.0%Recovered
100%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
11 28%
1–2 days
8 20%
3–7 days
6 15%
1–4 weeks
7 18%
Over a month
8 20%

How the animals did

Died
16 33%
Euthanised
33 67%

Problems reported at the same time

40 82%
11 22%
Behaviour change
9 18%
Weakness
9 18%
Tremors
8 16%
Didn't work as expected
7 14%
Diarrhea
6 12%

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
4
8–11 years
19
12+ years
19

About this medicine

Type: medicine.

Questions owners ask

Can Keppra cause death in dogs?
49 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Keppra in dogs · Medicines most reported with death