Lethargy after Keppra in dogs

The FDA has received 24 reports of lethargy in dogs after Keppra. That is 13% of all reports for this medicine, compared with 11% across reports for all dog medicines.

24Reports
79%Marked serious
4.2%Recovered
46%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
5 25%
1–2 days
4 20%
3–7 days
3 15%
1–4 weeks
2 10%
Over a month
6 30%

How the animals did

Recovered
1 4.2%
Still unwell when reported
9 38%
Died
6 25%
Euthanised
5 21%
Not known
3 13%

Problems reported at the same time

11 46%
10 42%
Loss of appetite
10 42%
Diarrhea
9 38%
Wobbliness (ataxia)
7 29%
Tremors
5 21%
Weakness
5 21%

Age of the animals

Under 1 year
1
1–3 years
1
4–7 years
2
8–11 years
13
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Keppra cause lethargy in dogs?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Keppra in dogs · Medicines most reported with lethargy