Vocalising after Imidacloprid in dogs

The FDA has received 46 reports of vocalising in dogs after Imidacloprid. That is 2.4% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

46Reports

24%Marked serious

15%Recovered

6.5%Died or euthanised

Same dayTypical onset

How soon it started

Same day

24 55%

1–2 days

15 34%

3–7 days

4 9.1%

1–4 weeks

1 2.3%

Over a month

0 0.0%

How the animals did

Recovered

7 15%

Still unwell when reported

9 20%

Died

2 4.3%

Euthanised

1 2.2%

Not known

27 59%

Problems reported at the same time

11 24%

10 22%

10 22%

9 20%

Restlessness or agitation

8 17%

Tremors

8 17%

Didn't stop fleas

7 15%

Breathing problems

7 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Questions owners ask

Can Imidacloprid cause vocalising in dogs?: 46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Spinosad (Comfortis) 586 reports · 1.0% of its reports
Vocalising after Lufenuron + Milbemycin Oxime (Sentinel) 180 reports · 0.7% of its reports
Vocalising after Imidacloprid + Moxidectin (Advantage Multi) 295 reports · 2.2% of its reports
Vocalising after Nitenpyram (Capstar) 262 reports · 2.4% of its reports
Vocalising after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 45 reports · 0.5% of its reports
Vocalising after Fipronil + S-methoprene (Frontline Plus) 67 reports · 2.3% of its reports
Vocalising after Flumethrin + Imidacloprid (Seresto) 53 reports · 2.3% of its reports
Vocalising after Fipronil 28 reports · 2.0% of its reports
Vocalising after Imidacloprid + Permethrin + Pyriproxyfen 29 reports · 3.9% of its reports
Vocalising after Cyphenothrin + Fipronil + S-methoprene 55 reports · 8.5% of its reports

All reported side effects of Imidacloprid in dogs · Medicines most reported with vocalising