Falling after Grapiprant (Galliprant) in dogs

The FDA has received 94 reports of falling in dogs after Grapiprant. That is 1.1% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

94Reports
55%Marked serious
13%Recovered
28%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
19 25%
1–2 days
6 7.9%
3–7 days
12 16%
1–4 weeks
11 14%
Over a month
28 37%

How the animals did

Recovered
12 13%
Still unwell when reported
40 43%
Died
6 6.4%
Euthanised
20 21%
Not known
16 17%

Problems reported at the same time

Weakness
33 35%
Death
26 28%
Loss of appetite
22 23%
Lethargy
15 16%
Diarrhea
13 14%
Behaviour change
12 13%
Tremors
11 12%
Liver problems
10 11%

Age of the animals

Under 1 year
2
1–3 years
0
4–7 years
3
8–11 years
19
12+ years
69

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause falling in dogs?
94 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Falling with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with falling