Liver problems after Fentanyl in dogs

78 reports to the FDA describe liver problems in dogs given Fentanyl. That is 12% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports
83%Marked serious
6.4%Recovered
60%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
8 13%
1–2 days
17 28%
3–7 days
11 18%
1–4 weeks
9 15%
Over a month
15 25%

How the animals did

Recovered
5 6.4%
Still unwell when reported
17 22%
Died
14 18%
Euthanised
33 42%
Not known
9 12%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
14
4–7 years
24
8–11 years
28
12+ years
11

About this medicine

Type: medicine.

Questions owners ask

Can Fentanyl cause liver problems in dogs?
78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Fentanyl in dogs · Medicines most reported with liver problems