Liver problems after Famotidine in dogs

The FDA has received 603 reports of liver problems in dogs after Famotidine. That is 23% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

603Reports
70%Marked serious
11%Recovered
41%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
78 15%
1–2 days
75 15%
3–7 days
93 18%
1–4 weeks
155 30%
Over a month
108 21%

How the animals did

Recovered
63 10%
Recovered with lasting effects
4 0.7%
Still unwell when reported
236 39%
Died
74 12%
Euthanised
176 29%
Not known
50 8.3%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
78
4–7 years
161
8–11 years
239
12+ years
97

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause liver problems in dogs?
603 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Famotidine in dogs · Medicines most reported with liver problems