Liver problems after Epinephrine in dogs

70 reports to the FDA describe liver problems in dogs given Epinephrine. That is 22% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

70Reports
100%Marked serious
7.1%Recovered
43%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
42 67%
1–2 days
7 11%
3–7 days
4 6.3%
1–4 weeks
4 6.3%
Over a month
6 9.5%

How the animals did

Recovered
5 7.1%
Still unwell when reported
27 39%
Died
17 24%
Euthanised
13 19%
Not known
8 11%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
23
4–7 years
17
8–11 years
19
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Epinephrine cause liver problems in dogs?
70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Epinephrine in dogs · Medicines most reported with liver problems