Doxycycline side effects in dogs

4,014 reports sent to the FDA between 1997 and 2026 involve Doxycycline in dogs. The most reported problems were vomiting, loss of appetite, lethargy. 58% were marked serious, and where it was recorded, signs eased after stopping the medicine in 67% of cases.

4,014Reports
58%Marked serious
2.7%Only medicine involved
14%Recovered
13%Died or euthanised
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About this medicine

Doxycycline treats bacterial and tick-borne infections.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
11 0.3%

How soon problems started

Same day
367 12%
1–2 days
217 7.3%
3–7 days
241 8.1%
1–4 weeks
463 16%
Over a month
1,675 57%

Time from the first dose to the first sign, where both dates were reported (2,963 reports).

How the animals did

Recovered
538 13%
Recovered with lasting effects
25 0.6%
Still unwell when reported
1,971 49%
Died
233 5.8%
Euthanised
290 7.2%
Not known
957 24%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other antibiotics for dogs