Doxycycline side effects in dogs
4,014 reports sent to the FDA between 1997 and 2026 involve Doxycycline in dogs. The most reported problems were vomiting, loss of appetite, lethargy. 58% were marked serious, and where it was recorded, signs eased after stopping the medicine in 67% of cases.
4,014Reports
58%Marked serious
2.7%Only medicine involved
14%Recovered
13%Died or euthanised
About this medicine
Doxycycline treats bacterial and tick-borne infections.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (2,963 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 331 reports
- German Shepherd Dog 161 reports
- Beagle 120 reports
- Chihuahua 115 reports
- Bull - American Pit Terrier 115 reports
- Golden Retriever 107 reports
- Australian Shepherd Dog 87 reports
- Dachshund 62 reports
- Boxer (german Boxer) 59 reports
- Pit Bull 59 reports
Other antibiotics for dogs
Amoxicillin + Clavulanate (Clavamox)5,376 reports · 33% seriousCefovecin (Convenia)3,789 reports · 39% seriousEnrofloxacin (Baytril)3,769 reports · 55% seriousMetronidazole3,090 reports · 55% seriousAmoxicillin1,349 reports · 49% seriousEnrofloxacin + Silver Sulfadiazine210 reports · 71% seriousEnrofloxacin + Ketoconazole + Triamcinolone95 reports · 29% serious
