Didn't work as expected after Doxycycline in dogs

428 reports to the FDA describe didn't work as expected in dogs given Doxycycline. That is 11% of all reports for this medicine, compared with 13% across reports for all dog medicines.

428Reports

46%Marked serious

6.3%Recovered

16%Died or euthanised

101 daysTypical onset

How soon it started

Same day

26 9.3%

1–2 days

9 3.2%

3–7 days

5 1.8%

1–4 weeks

41 15%

Over a month

198 71%

How the animals did

Recovered

25 5.8%

Recovered with lasting effects

2 0.5%

Still unwell when reported

225 53%

Died

24 5.6%

Euthanised

45 11%

Not known

107 25%

Problems reported at the same time

Didn't prevent heartworm

79 18%

73 17%

68 16%

66 15%

64 15%

63 15%

44 10%

34 7.9%

Age of the animals

Under 1 year

1–3 years

135

4–7 years

127

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause didn't work as expected in dogs?: 428 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 101 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Amoxicillin + Clavulanate (Clavamox) 1,093 reports · 20% of its reports
Didn't work as expected after Cefovecin (Convenia) 584 reports · 15% of its reports
Didn't work as expected after Enrofloxacin (Baytril) 368 reports · 9.8% of its reports
Didn't work as expected after Metronidazole 407 reports · 13% of its reports
Didn't work as expected after Amoxicillin 145 reports · 11% of its reports
Didn't work as expected after Enrofloxacin + Silver Sulfadiazine 32 reports · 15% of its reports
Didn't work as expected after Enrofloxacin + Ketoconazole + Triamcinolone 20 reports · 21% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with didn't work as expected