Didn't work as expected after Enrofloxacin + Silver Sulfadiazine in dogs

32 reports to the FDA describe didn't work as expected in dogs given Enrofloxacin + Silver Sulfadiazine. That is 15% of all reports for this medicine, compared with 13% across reports for all dog medicines.

32Reports
56%Marked serious
13%Recovered
0.0%Died or euthanised
12 daysTypical onset
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How soon it started

Same day
5 19%
1–2 days
3 11%
3–7 days
5 19%
1–4 weeks
6 22%
Over a month
8 30%

How the animals did

Recovered
4 13%
Still unwell when reported
6 19%
Not known
22 69%

Problems reported at the same time

6 19%
Abnormal cytology
5 16%
Ear infection
4 13%
Ear discharge
4 13%
Behaviour change
4 13%
Culture/titer data abnormal
3 9.4%
Otorrhoea
3 9.4%

Age of the animals

Under 1 year
1
1–3 years
5
4–7 years
7
8–11 years
10
12+ years
4

About this medicine

Enrofloxacin treats bacterial infections.

Questions owners ask

Can Enrofloxacin + Silver Sulfadiazine cause didn't work as expected in dogs?
32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 12 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Enrofloxacin + Silver Sulfadiazine in dogs · Medicines most reported with didn't work as expected