Kidney problems after Doxycycline in dogs

236 reports to the FDA describe kidney problems in dogs given Doxycycline. That is 5.9% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

236Reports

80%Marked serious

2.5%Recovered

49%Died or euthanised

27 daysTypical onset

How soon it started

Same day

17 9.4%

1–2 days

15 8.3%

3–7 days

22 12%

1–4 weeks

40 22%

Over a month

86 48%

How the animals did

Recovered

6 2.5%

Still unwell when reported

93 39%

Died

41 17%

Euthanised

74 31%

Not known

22 9.3%

Problems reported at the same time

141 60%

135 57%

115 49%

102 43%

102 43%

97 41%

67 28%

58 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause kidney problems in dogs?: 236 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Amoxicillin + Clavulanate (Clavamox) 428 reports · 8.0% of its reports
Kidney problems after Cefovecin (Convenia) 261 reports · 6.9% of its reports
Kidney problems after Enrofloxacin (Baytril) 304 reports · 8.1% of its reports
Kidney problems after Metronidazole 337 reports · 11% of its reports
Kidney problems after Amoxicillin 152 reports · 11% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with kidney problems