Kidney problems after Amoxicillin in dogs

The FDA has received 152 reports of kidney problems in dogs after Amoxicillin. That is 11% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

152Reports

70%Marked serious

3.9%Recovered

45%Died or euthanised

8 daysTypical onset

How soon it started

Same day

16 16%

1–2 days

14 14%

3–7 days

21 21%

1–4 weeks

28 27%

Over a month

23 23%

How the animals did

Recovered

5 3.3%

Recovered with lasting effects

1 0.7%

Still unwell when reported

46 30%

Died

21 14%

Euthanised

48 32%

Not known

31 20%

Problems reported at the same time

91 60%

88 58%

78 51%

69 45%

69 45%

40 26%

36 24%

34 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause kidney problems in dogs?: 152 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Amoxicillin + Clavulanate (Clavamox) 428 reports · 8.0% of its reports
Kidney problems after Doxycycline 236 reports · 5.9% of its reports
Kidney problems after Cefovecin (Convenia) 261 reports · 6.9% of its reports
Kidney problems after Enrofloxacin (Baytril) 304 reports · 8.1% of its reports
Kidney problems after Metronidazole 337 reports · 11% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with kidney problems